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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC63
All Species:
32.73
Human Site:
T294
Identified Species:
55.38
UniProt:
Q9UGP8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGP8
NP_009145.1
760
87997
T294
K
K
N
E
P
P
L
T
C
P
Y
S
L
K
A
Chimpanzee
Pan troglodytes
XP_001148185
760
87976
T294
K
K
N
E
P
P
L
T
C
P
Y
S
L
K
A
Rhesus Macaque
Macaca mulatta
XP_001091991
689
79874
N289
G
S
I
N
L
K
K
N
E
P
P
L
T
C
P
Dog
Lupus familis
XP_532252
850
96553
T384
K
K
N
E
P
P
L
T
C
P
Y
S
L
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHE0
760
87823
T294
K
K
N
E
P
P
L
T
C
P
Y
S
L
K
A
Rat
Rattus norvegicus
NP_001101107
727
83574
T294
K
K
N
E
P
P
L
T
C
P
Y
S
L
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511532
775
89598
T309
K
K
N
E
P
P
L
T
C
P
Y
S
L
K
A
Chicken
Gallus gallus
XP_419802
759
87965
T294
K
K
N
E
P
P
L
T
C
P
Y
S
L
K
A
Frog
Xenopus laevis
NP_001088542
754
87189
T294
K
K
N
E
P
P
L
T
C
P
Y
S
L
K
T
Zebra Danio
Brachydanio rerio
XP_002666271
754
86861
C294
K
K
K
E
P
P
F
C
Y
P
Y
S
L
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648111
753
85835
C296
K
C
K
E
H
P
L
C
R
M
Y
S
I
K
A
Honey Bee
Apis mellifera
XP_395961
751
87148
C296
K
N
K
A
I
A
L
C
D
S
Y
D
G
S
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793617
800
91710
D311
P
P
K
T
L
D
V
D
R
L
Y
V
V
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14906
663
75326
S264
V
T
A
S
N
F
V
S
N
L
V
N
Y
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
89.3
88.3
N.A.
96.1
91.8
N.A.
86.8
91.5
83.4
72.3
N.A.
44
42.3
N.A.
40.8
Protein Similarity:
100
99.8
89.8
89.1
N.A.
98.5
94.2
N.A.
91.8
95.7
91.8
84.7
N.A.
63.6
62.3
N.A.
59
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
93.3
73.3
N.A.
53.3
20
N.A.
13.3
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
93.3
73.3
N.A.
60
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
65
% A
% Cys:
0
8
0
0
0
0
0
22
58
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
8
0
8
8
0
0
8
0
0
0
% D
% Glu:
0
0
0
72
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
79
65
29
0
0
8
8
0
0
0
0
0
0
86
8
% K
% Leu:
0
0
0
0
15
0
72
0
0
15
0
8
65
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
58
8
8
0
0
8
8
0
0
8
0
0
0
% N
% Pro:
8
8
0
0
65
72
0
0
0
72
8
0
0
0
15
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% R
% Ser:
0
8
0
8
0
0
0
8
0
8
0
72
0
8
0
% S
% Thr:
0
8
0
8
0
0
0
58
0
0
0
0
8
0
8
% T
% Val:
8
0
0
0
0
0
15
0
0
0
8
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
86
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _